Author

A. W. Lohse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Butler· 1 shared A. M. Moon· 1 shared A. P. Davenport· 1 shared A. Volmari· 1 shared C. J. E. Watson· 1 shared D. Muraro· 1 shared E. Barnes· 1 shared F. Sampaziotis· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

A. J. Butler

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2 papers

Recent·Most cited

FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome

T. Brevini, M. Maes, G. J. Webb, W. T. H. Gelson, S. Forrest, P. Mlcochova, S. Dillon, S. Varankar, M. Darvish-Damavandi, V. L. Mulcahy, R. E. Kuc, T. L. Williams, V. Galanakis, M. Vila-Gonzalez, O. C. Tysoe, , F. Sampaziotis

This study shows FXR inhibition lowers ACE2 expression, reduces SARS-CoV-2 infection, and correlates with better clinical outcomes in COVID-19.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology

Leukocyte-derived High-mobility group box 1 controls innate immune responses against Listeria monocytogenes.

A. Volmari, K. Foelsch, K. Yan, M. Qi, K. Bartels, S. Kondratowicz, M. Boettcher, M. Nishibori, K. Liu, R. F. Schwabe, A. W. Lohse, S. Huber, H.-W. Mittruecker, P. Huebener

This study shows that HMGB1 from leukocytes is critical for immune responses against Listeria monocytogenes, while hepatocyte HMGB1 is not essential for moderate infections but may contribute to excessive inflammation in severe cases.

bioRxiv · Oct 8, 2019 · PreprintImmunology