Molecular definition of the BAK:VDAC2 interaction as a target to manipulate apoptosis
Z. Yuan, M. F. van Delft, M. X. Li, F. Sumardy, B. J. Smith, D. C. S. Huang, G. Lessene, Y. Khakham, R. Jin, S. He, N. A. Smith, R. Birkinshaw, P. E. Czabotar, G. Dewson
This study identifies key residues in the BAK:VDAC2 interaction, showing that disrupting this interaction can inhibit or promote apoptosis depending on the context.
bioRxiv · Dec 13, 2023 · PreprintCell Biology