Author

N. A. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:multiple species· 1 Assay:proteomics· 1

Frequent Co-Authors

A. N. Bade· 1 shared A. Szlachetka· 1 shared B. J. Edagwa· 1 shared B. J. Smith· 1 shared B. L. Dyavar Shetty· 1 shared B. Sillman· 1 shared D. C. S. Huang· 1 shared D. Kumar· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. N. Bade

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular definition of the BAK:VDAC2 interaction as a target to manipulate apoptosis

Z. Yuan, M. F. van Delft, M. X. Li, F. Sumardy, B. J. Smith, D. C. S. Huang, G. Lessene, Y. Khakham, R. Jin, S. He, N. A. Smith, R. Birkinshaw, P. E. Czabotar, G. Dewson

This study identifies key residues in the BAK:VDAC2 interaction, showing that disrupting this interaction can inhibit or promote apoptosis depending on the context.

bioRxiv · Dec 13, 2023 · PreprintCell Biology

Lipophilic Nanocrystal Prodrug-Release Defines the Extended Pharmacokinetic Profiles of a Year-Long Cabotegravir

N. Gauram, J. M. McMillan, D. Kumar, A. N. Bade, Q. Pan, T. A. Kulkarni, W. Li, N. A. Smith, B. L. Dyavar Shetty, B. Sillman, A. Szlachetka, B. J. Edagwa, H. E. Gendelman, Y. Alnouti

This study demonstrates that a nanoformulated CAB prodrug (NM2CAB) maintains plasma levels above the inhibitory concentration for up to one year, with sustained drug retention in tissues and macrophages.

Nature Communications · Jun 8, 2021Peer-reviewedPharmacology & Toxicology