Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2
F. Touret, J.-S. Driouich, M. Cochin, P. R. Petit, M. Gilles, K. Barthelemy, G. Moureau, F.-X. MAHON, D. Malvy, C. Solas, X. de Lamballerie, A. Nougairede
This study evaluates Imatinib's antiviral potential against SARS-CoV-2 in vitro and in vivo, finding it ineffective in key models despite plasma and lung concentrations.
bioRxiv · Nov 17, 2020Microbiology