B. Ghesquiere

This study identifies Nprl3 as a key regulator of erythroid metabolism, showing its role in coupling metabolic and developmental processes during erythropoiesis.

This study identifies HIF-1α-mediated metabolic reprogramming as a mechanism controlling the transition of precursor T cells to terminally exhausted T cells in chronic infections and cancer.

This study uses 13C metabolomics and transcriptomics to analyze metabolic changes in CD8+ T cells during differentiation, identifying key metabolic checkpoints and their role in exhaustion.

This paper shows that BAPTAi inhibits PFKFB3, reducing mTORC1-driven Mcl-1 translation and killing Mcl-1-dependent cancer cells, independent of Ca2+ signaling.

This study shows that combining tyrosine kinase inhibitors with Kidrolase targets glutamine metabolism and enhances CML stem cell eradication.

This study shows that Exostosin-1 glycosyltransferase regulates ER morphology and dynamics, affecting cell size and metabolic processes in mammalian cells.