Cancer BiologybioRxivPreprint
The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Metformin
Guillaume Lefrançois, Emilie Lavallée, Marie‐Camille Rowell…·Gerardo Ferbeyre
This paper identifies ATP5I as a target of metformin, showing its role in mediating metabolic and antiproliferative effects through mitochondrial dysfunction and altered ATP synthase oligomerization.
DOI 10.1101/2024.09.20.614047