Fei Luo

Synchronized Latency Reversal and Immune Clearance by a Multifunctional Fusion Protein Enables HIV-1 Reservoir Reduction

This paper develops a fusion protein that reactivates HIV-1 latency and enhances immune clearance, reducing viral reservoirs in HIV-infected individuals and humanized mice.

Dual Control of Low-Density Lipoprotein Cholesterol Levels by ANGPTL3 and ANGPTL8

This study investigates how ANGPTL3 and ANGPTL8 regulate LDL cholesterol levels through their cleavage products and interactions with lipases, showing that both proteins are required for maximal lipolysis inhibition.

Identification of a Highly Expressed Gene Cluster Likely Coding for Benzene Activation Enzymes in a Methanogenic Enrichment Culture

The paper identifies two gene clusters in a methanogenic enrichment culture that likely code for benzene activation enzymes, providing genetic and proteomic evidence for anaerobic benzene degradation mechanisms.

CARP Protects Against Doxorubicin-induced Cardiotoxicity through NRF1-driven Mitochondrial Homeostasis

This study shows CARP protects against doxorubicin-induced cardiotoxicity by maintaining mitochondrial homeostasis through NRF1 signaling.

cfGWAS reveal genetic basis of cell-free DNA features

This study conducts the first GWAS on cell-free DNA (cfDNA) features in pregnant women, identifying 84 genetic loci and revealing causal relationships between hematological indicators and cfDNA biology.