GenomicsbioRxivPreprint
Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates
Fabrizio Olmeda, Tim Lohoff, Stephen J. Clark…·Steffen Rulands
This paper develops a framework to infer spatio-temporal processes in the nucleus from single-cell methylome data, showing feedback between DNA methylation and chromatin condensates during pluripotency exit.