Author

Flor A. Gowans

Innovative Genomics Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Belen E. Altamirano PoblanoiD· 1 shared Daniel K. NomuraiD· 1 shared Ingrid E. WertziD· 1 shared Justin Hatcher· 1 shared Nafsika ForteiD· 1 shared Oscar W. Huang· 1 shared Yangzhi WangiD· 1 shared

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2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Belen E. Altamirano PoblanoORCID

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1 paper

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedJun 6, 2024

Covalent Degrader of the Oncogenic Transcription Factor β-Catenin

Flor A. Gowans, Nafsika Forte, Justin Hatcher…·Daniel K. Nomura

This paper identifies a covalent degrader, EN83, that targets and degrades β-catenin by covalently binding to four cysteine residues, demonstrating a strategy to overcome the 'undruggable' challenge of transcription factors.

31 citations

humanproteomics

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