Author
University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Nefeli Skoufou-Papoutsaki, Sam Adler, Shenay Mehmed…·Douglas J. Winton
The paper investigates how PTEN and ARID1A haploinsufficiency in colonic epithelium contributes to oncogenic transformation by altering clone dynamics and creating a pro-tumorigenic microenvironment.
Rachel D. Edgar, Francesca Marta Perrone, April Rose Foster…·Matthias Zilbauer
This study shows that long-term culture of human intestinal organoids leads to DNA methylation changes, altered gene expression, and functional shifts, suggesting potential confounding effects in research.
Dawei Sun, Lewis Evans, Francesca Marta Perrone…·Emma L. Rawlins
This paper develops a genetic toolbox for tissue-derived human organoids, enabling efficient gene manipulation through CRISPR-based methods and flow cytometry.