Pan-cancer analysis of the metabolic reaction network
This study analyzes metabolic networks across 917 tumors and normal tissues, finding core reactions shared between tumors and normal tissues, with some cancer-specific reactions identified.
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This study analyzes metabolic networks across 917 tumors and normal tissues, finding core reactions shared between tumors and normal tissues, with some cancer-specific reactions identified.
Amir Feizi, Francesco Gatto, Mathias Uhlen, Jens Nielsen
The paper identifies tissue-specific fine-tuning of the secretory pathway by analyzing transcriptome data across 30 human tissues, revealing subnetwork-specific expression patterns and their correlation with post-translational modifications.