Cancer BiologyiSciencePeer-reviewed
An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCC.
Maroussia M. P. Ganpat, Francisco Morales-Rodriguez, Nhung Pham…·Jarno Drost
This study creates an engineered tumor organoid model of tRCC using SFPQ-TFE3 fusion expression, revealing epithelium-to-mesenchymal differentiation and Wnt signaling involvement in tumor transformation.
5 citations