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Frank M. Wu

Oklahoma Medical Research Foundation

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Approach:experimental assay· 1 Organism:yeast· 1

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Dean DawsoniD· 1 shared Jingrong CheniD· 1 shared Susannah RankiniD· 1 shared

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Dean DawsonORCID

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GeneticsbioRxivPreprintFeb 10, 2018

Cornelia de Lange Syndrome-associated mutations in Smc1 cause both sister chromatid cohesion and cohesion-independent defects

Jingrong Chen, Frank M. Wu, Dean Dawson, Susannah Rankin

The paper uses budding yeast to assess the impact of CdLS-associated Smc1 mutations on cohesin function, identifying two classes of mutations with distinct effects on chromosome segregation and cohesion.

DOI 10.1101/263418

yeastexperimental assay

𝕏 PostBluesky