Author

Frecia Rodriguez

Inserm

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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Agathe Bernand· 1 shared Ashwin JainarayananiD· 1 shared Brienne McKenzieiD· 1 shared Claire C. StatoniD· 1 shared Emma CiniiD· 1 shared Laurence LamantiD· 1 shared Lina Chen· 1 shared Lucie DemeerssemaniD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Agathe Bernand

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintMay 24, 2024

Perforin-mediated pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway

Brienne McKenzie, Marie-Pierre Puisségur, Lucie Demeersseman…·Salvatore Valitutti

This study shows perforin triggers pyroptosis in target cells by activating the NLRP3/caspase-1/gasdermin D pathway, while sustained CTL interaction leads to apoptosis.

1 citation

experimental assayhost-pathogen & immune response

𝕏 PostBluesky