Author

Laurence Lamant

Centre National de la Recherche ScientifiqueORCID 0000-0002-1123-7658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2

Frequent Co-Authors

Fabienne MeggettoiD· 3 shared Sandra DailhauiD· 3 shared Chloé BessièreiD· 2 shared Loélia BabiniD· 2 shared Lola Colras· 2 shared Steffen FuchsiD· 2 shared Stéphane PyronnetiD· 2 shared Agathe Bernand· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

Fabienne MeggettoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 12, 2026

NPM1::ALK fusion-derived circular RNAs drive aggressiveness in ALK-positive anaplastic large cell lymphoma

Loelia BABIN, Lola Colras, Sandra Dailhau…·Fabienne Meggetto

The paper identifies NPM1::ALK-derived circular RNAs that promote aggressiveness in ALK-positive anaplastic large cell lymphoma by modulating cytokine signaling and myeloid remodeling.

DOI 10.64898/2026.11.09.765349

humanlong-read sequencing

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Cancer BiologyLeukemiaPeer-reviewedJun 26, 2026

CircZBTB46, a promising therapeutic target in crizotinib resistant ALK-positive T lymphomas

Loélia Babin, Elissa Andraos, Steffen Fuchs…·Fabienne Meggetto

The paper identifies circZBTB46 as a driver of crizotinib resistance in ALK-positive lymphomas and shows its targeting restores drug sensitivity.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 20, 2026

Tumor microenvironment signature associated with morphology in systemic ALK-positive anaplastic large cell lymphoma

Chloé Bessière, Loélia Babin, Sandra Dailhau…·Laurence Lamant

The paper identifies tumor microenvironment signatures linked to morphology and prognosis in ALK-positive anaplastic large cell lymphoma using computational analysis of gene expression data.

DOI 10.64898/2026.01.20.700117

humanbulk RNA-seq

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Cell BiologybioRxivPreprintMay 24, 2024

Perforin-mediated pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway

Brienne McKenzie, Marie-Pierre Puisségur, Lucie Demeersseman…·Salvatore Valitutti

This study shows perforin triggers pyroptosis in target cells by activating the NLRP3/caspase-1/gasdermin D pathway, while sustained CTL interaction leads to apoptosis.

1 citation

experimental assayhost-pathogen & immune response

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