Cancer BiologybioRxivPreprint
Identification of the KIF18A alpha-4 helix as a therapeutic target for chromosomally unstable tumor cells
Katherine Schutt, Katelyn A. Queen, Kira Fisher…·Jason Stumpff
This study identifies the KIF18A alpha-4 helix as a therapeutic target, showing that mutations or inhibitors targeting this region disrupt proliferation of chromosomally unstable tumor cells.
DOI 10.1101/2023.10.16.562576