Dietary methionine restriction targets one carbon metabolism in humans and produces broad therapeutic responses in cancer
X. Gao, S. M. Sanderson, Z. Dai, M. A. Reid, D. E. Cooper, M. Lu, J. P. Richie, A. Ciccarella, A. Calcagnotto, P. Mikhael, S. J. Mentch, J. Liu, G. Ables, D. G. Kirsch, D. Hsu, , J. W. Locasale
This study shows that dietary methionine restriction affects one carbon metabolism in humans and produces therapeutic responses in cancer by altering metabolic pathways.
bioRxiv · May 4, 2019 · PreprintCancer Biology