Author

P. Mikhael

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Calcagnotto· 1 shared A. Ciccarella· 1 shared C. Van Dongen· 1 shared D. E. Cooper· 1 shared D. G. Kirsch· 1 shared D. Hsu· 1 shared G. Ables· 1 shared G. Zylberberg· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Calcagnotto

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Author profile →

2 papers

Recent·Most cited

Protein codes promote selective subcellular compartmentalization

H. Kilgore, I. Chinn, P. Mikhael, I. Mitnikov, C. Van Dongen, G. Zylberberg, L. Afeyan, S. Banani, S. Wilson-Hawken, T. Lee, R. Barzialy, R. Young

This study introduces ProtGPS, a protein language model that predicts subcellular compartment localization and identifies mutations affecting this process.

bioRxiv · Apr 15, 2024Biochemistry

Dietary methionine restriction targets one carbon metabolism in humans and produces broad therapeutic responses in cancer

X. Gao, S. M. Sanderson, Z. Dai, M. A. Reid, D. E. Cooper, M. Lu, J. P. Richie, A. Ciccarella, A. Calcagnotto, P. Mikhael, S. J. Mentch, J. Liu, G. Ables, D. G. Kirsch, D. Hsu, , J. W. Locasale

This study shows that dietary methionine restriction affects one carbon metabolism in humans and produces therapeutic responses in cancer by altering metabolic pathways.

bioRxiv · May 4, 2019 · PreprintCancer Biology