Voltage-gated T-type calcium channel blockers reduce apoptotic body-mediated SARS-CoV-2 cell-to-cell spread and subsequent cytokine storm
T. K. Phan, D. Sheerin, B. Shi, M. Dayton, L. Mackiewicz, D. C. Ozkocak, G. Atkin-Smith, N. Peton, O. Audi, R. Tixeira, G. Ashdown, K. C. Davidson, M. Doerflinger, A. K. Coussens, I. K. H. Poon
This study shows that T-type calcium channel blockers reduce SARS-CoV-2 spread via apoptotic bodies and limit cytokine storms in macrophages.
bioRxiv · Nov 3, 2023 · PreprintCell Biology