Author

L. Mackiewicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. K. Coussens· 1 shared B. C. Duckworth· 1 shared B. J. Broomfield· 1 shared B. Shi· 1 shared C. Alvarado· 1 shared C. W. Tan· 1 shared D. C. Ozkocak· 1 shared D. Sheerin· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. K. Coussens

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

B. J. Broomfield, C. W. Tan, R. Z. Qin, B. C. Duckworth, C. Alvarado, L. Dalit, J. Chen, L. Mackiewicz, H. Muramatsu, M. Pellegrini, K. Rogers, W. J. Moon, S. L. Nutt, M. J. Davis, N. Pardi, , J. R. Groom

This paper shows that temporarily blocking type I interferon during viral infection boosts CD8+ T cell memory and vaccine effectiveness by promoting TSCM cell formation.

bioRxiv · Jun 26, 2024Immunology

Voltage-gated T-type calcium channel blockers reduce apoptotic body-mediated SARS-CoV-2 cell-to-cell spread and subsequent cytokine storm

T. K. Phan, D. Sheerin, B. Shi, M. Dayton, L. Mackiewicz, D. C. Ozkocak, G. Atkin-Smith, N. Peton, O. Audi, R. Tixeira, G. Ashdown, K. C. Davidson, M. Doerflinger, A. K. Coussens, I. K. H. Poon

This study shows that T-type calcium channel blockers reduce SARS-CoV-2 spread via apoptotic bodies and limit cytokine storms in macrophages.

bioRxiv · Nov 3, 2023 · PreprintCell Biology