BiochemistrybioRxivPreprint
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms
G. Bendzunas, D. P. Byrne, S. Shrestha…·N. Kannan
This study investigates how redox regulation via cysteine oxidation controls BRSK1/2 kinase activity, revealing conserved mechanisms that modulate catalytic function through disulfide bond formation and salt bridge disruption.
DOI 10.1101/2023.10.05.561145