Influence of mutagenic versus non-mutagenic pre-operative chemotherapy on the immune infiltration of breast cancer
A.-M. Tokes, O. Rusz, G. Cserni, E. Toth, G. Rubovszky, T. Tokes, L. Vizkeleti, L. Reiniger, R. Koszo, Z. Kahan, J. Kulka, M. Donia, A. Voros, Z. Szallasi
This study examines how mutagenic and non-mutagenic pre-operative chemotherapy affects immune infiltration in breast cancer, finding that increased stromal tumor-infiltrating lymphocytes (StrTIL) correlates with better distant metastasis-free survival in HR-negative cases.
bioRxiv · Oct 29, 2018Cancer Biology