L. Vizkeleti

This paper identifies NER deficiency as a targetable vulnerability in ccRCC, showing that 10% of patients may respond to irofulven based on mutational signatures and PTGR1 expression.

This study investigates the epigenetic regulation of Septin9 variants in colorectal cancer, finding hypermethylation at the v2 promoter leads to alternative transcription and potential functional differences.

This paper analyzes proteogenomic data from melanoma patients to show how metastatic melanoma alters metabolism and immune responses to evade immune detection.

This study examines how mutagenic and non-mutagenic pre-operative chemotherapy affects immune infiltration in breast cancer, finding that increased stromal tumor-infiltrating lymphocytes (StrTIL) correlates with better distant metastasis-free survival in HR-negative cases.