Cancer BiologybioRxiv
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
A. B. Brinkman, S. Nik-Zainal, F. Simmer…·H. G. Stunnenberg
The paper shows PMDs are hypervariable in breast cancer and drive CGI hypermethylation, but do not significantly repress cancer genes.
DOI 10.1038/s41467-019-09828-0