Author

G. E. Duran

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. I. Sikic· 1 shared J.-P. Jaffrezou· 1 shared K. G. Chen· 1 shared K. L. Ross· 1 shared L. M. Huff· 1 shared M. J. Mogul· 1 shared N. J. Lacayo· 1 shared T. Fojo· 1 shared

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2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

B. I. Sikic

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1 paper

Recent·Most cited

Cancer BiologybioRxivOct 28, 2019

The Genomic Stability at the Coding Regions of the Multidrug Transporter Gene ABCB1: Insights into the Development of Alternative Drug Resistance Mechanisms in Human Leukemia Cells

K. G. Chen, G. E. Duran, M. J. Mogul…·B. I. Sikic

This study develops drug-resistant leukemia cell lines to investigate the mechanisms of cyclosporine's effect on multidrug resistance, finding that ABCB1 remains genetically stable and non-P-gp mechanisms contribute to resistance.

DOI 10.20517/cdr.2020.51

humanbulk RNA-seq

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