ImmunologybioRxiv
HIV reservoir size is determined prior to ART initiation and linked to CD8 T cell activation and memory expansion
G. E. Martin, M. Pace, F. Shearer…·CHERUB investigators
This study finds that pre-ART HIV DNA levels predict reservoir size one year after treatment initiation during primary HIV infection, linked to CD8 T cell activation and memory expansion.
DOI 10.1093/infdis/jiz563