Author

G. Hartleben

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. F. Calkhoven· 1 shared G. Kortman· 1 shared H. R. Zuidhof· 1 shared M. A. Zaini· 1 shared M. G. S. Rutten· 1 shared M. J. C. Broekhuis· 1 shared T. Ackermann· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

C. F. Calkhoven

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintOct 9, 2020

C/EBPβ-LIP dually activates glycolysis and the malate aspartate shuttle to maintain NADH/NAD+ homeostasis

T. Ackermann, H. R. Zuidhof, G. Kortman…·C. F. Calkhoven

This study shows that C/EBPβ-LIP activates both glycolysis and the malate-aspartate shuttle to maintain NADH/NAD+ homeostasis, and inhibiting both could be a strategy for cancer treatment.

DOI 10.1101/2020.10.09.333104

experimental assaycancer & tumor microenvironment

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