G. Janson

Direct Generation of Protein Conformational Ensembles via Machine Learning

This paper shows that machine learning can generate protein conformational ensembles without simulation, using a transformer-based GAN trained on simulation data.

Revisiting degron motifs in human AURKA required for its targeting by APC/C-FZR1

This study redefines AURKA degron motifs, showing the N-terminal A-box functions as a D-box and the C-terminal D-box is not a degron but a structural motif essential for AURKA's active conformation.