Cell BiologybioRxiv
Revisiting degron motifs in human AURKA required for its targeting by APC/C-FZR1
C. Lindon, A. A. Abdelbaki, C. Ascanelli…·A. Paiardini
This study redefines AURKA degron motifs, showing the N-terminal A-box functions as a D-box and the C-terminal D-box is not a degron but a structural motif essential for AURKA's active conformation.
DOI 10.26508/lsa.202201372