Author

G. Karpen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:Drosophila· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Janssen· 1 shared A. Kendek· 1 shared A. Sandron· 1 shared D. Jost· 1 shared I. Gooijers· 1 shared J.-P. Lambooij· 1 shared L. Brennan· 1 shared L. de Groot· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Janssen

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Author profile →

2 papers

Recent·Most cited

DNA Double-Strand Break Movement in Heterochromatin Depends on the Histone Acetyltransferase dGcn5.

A. Kendek, A. Sandron, J.-P. Lambooij, S. U. Colmenares, S. M. Pociunaite, I. Gooijers, L. de Groot, G. Karpen, A. Janssen

This study shows that dGcn5-mediated H3K9ac enrichment at heterochromatic DSBs is essential for their movement to the periphery and proper repair.

bioRxiv · Nov 30, 2023Cell Biology

HP1-driven phase separation recapitulates the thermodynamics and kinetics of heterochromatin condensate formation

M. M. Tortora, L. Brennan, G. Karpen, D. Jost

This paper investigates how HP1-driven phase separation forms PCH condensates in vivo, showing that HP1-chromatin interactions and genomic H3K9me2/3 distribution govern their thermodynamics and kinetics.

bioRxiv · Jul 11, 2022 · PreprintBiophysics