Author

M. M. Tortora

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Biophysics· 2

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Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Organism:Drosophila· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Jost· 2 shared A. Z. Abdulla· 1 shared C. Vaillant· 1 shared G. Karpen· 1 shared L. Brennan· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

D. Jost

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2 papers

Recent·Most cited

BiophysicsbioRxivJun 16, 2023

Topological constraints and finite-size effects in quantitative polymer models of chromatin organization

A. Z. Abdulla, M. M. Tortora, C. Vaillant, D. Jost

This paper investigates the minimal chromosome length needed for accurate polymer simulations of chromatin organization, showing how topological constraints and finite-size effects influence sub-chromosomal structure and dynamics.

DOI 10.1021/acs.macromol.3c01182

statistical modelchromatin & epigenetic regulation

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 11, 2022

HP1-driven phase separation recapitulates the thermodynamics and kinetics of heterochromatin condensate formation

M. M. Tortora, L. Brennan, G. Karpen, D. Jost

This paper investigates how HP1-driven phase separation forms PCH condensates in vivo, showing that HP1-chromatin interactions and genomic H3K9me2/3 distribution govern their thermodynamics and kinetics.

DOI 10.1101/2022.07.11.499635

Drosophilabiophysical modeling

𝕏 PostBluesky