Constitutive TRIM22 expression within the respiratory tract identifies tissue-specific and cell-type dependent intrinsic immune barriers to influenza A virus infection
M. Charman, S. McFarlane, J. K. Wojtus, E. Sloan, R. Dewar, G. Leeming, M. Al-Saadi, L. Hunter, M. Carroll, J. P. Stewart, P. Digard, E. Hutchinson, C. Boutell
This study identifies TRIM22 as a constitutively expressed antiviral factor in the respiratory tract that restricts influenza A virus infection independently of cytokine-mediated immunity.
bioRxiv · Jun 21, 2019 · PreprintImmunology