Author

L. Hunter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Ecology· 1 Immunology· 1 Paleontology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:human· 4 Organism:rat· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:non-human primate· 2 Assay:proteomics· 2

Frequent Co-Authors

E. Brunt· 3 shared H. E. Humphries· 3 shared K. A. Ryan· 3 shared K. R. Bewley· 3 shared L. Allen· 3 shared P. Brown· 3 shared R. Cobb· 3 shared S. Leung· 3 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

E. Brunt

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Highly Multiplexed Proteomic Analysis of HCMV-Infected Dendritic Cells Reveals Global Manipulation of Adaptive Immunity and Host Restriction of Viral Replication

L. Kerr-Jones, L. Soday, N. Cwyfan-Hughes, X. Wang, L. Hunter, R. Antrobus, K. Miners, K. Ladell, D. A. Price, C. A. Fielding, E. C. Wang, M. P. Weekes, R. J. Stanton

The paper uses proteomic analysis to study HCMV-infected dendritic cells, revealing how the virus manipulates adaptive immunity and restricts replication.

bioRxiv · Apr 30, 2024 · PreprintMicrobiology

Evidence for deliberate burial of the dead by Homo naledi

L. R. Berger, T. Makhubela, K. Molopyane, A. Kruger, P. Randolph-Quinney, M. Elliott, B. Peixotto, A. Fuentes, P. Tafforeau, V. Beyrand, K. Dollman, Z. Jinnah, A. Brewer Gillham, K. Broad, J. Brophy, , J. Hawks

This study presents evidence for deliberate burial of Homo naledi remains in South Africa's Rising Star cave system, suggesting mortuary behavior in this species.

bioRxiv · Jun 1, 2023 · PreprintPaleontology

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex

K. Nightingale, C. A. Fielding, C. Zerbe, L. Hunter, M. Potts, A. Fletcher-Etheringon, L. Nobre, E. C. Y. Wang, B. L. Strang, J. Houghton, R. Antrobus, N. M. Suarez, J. Nichols, A. J. Davison, R. J. Stanton, M. P. Weekes

This study identifies HCMV protein RL1 as a viral antagonist that degrades SLFN11 via CRL4 E3 ubiquitin ligase, revealing SLFN11's role in restricting HCMV infection.

bioRxiv · May 14, 2021Microbiology

Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

K. R. Bewley, K. E. R. Gooch, K. M. Thomas, S. R. Longet, N. Wiblin, L. Hunter, K. Chan, P. Brown, R. A. Russell, C. Ho, G. Slack, H. E. Humphries, L. Alden, L. Allen, M. Aram, , M. Carroll

This study evaluates vaccine-enhanced disease in ferrets and rhesus macaques after formalin-inactivated SARS-CoV-2 vaccination, finding mild transient lung pathology but no significant enhancement.

bioRxiv · Dec 21, 2020Pathology

Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19.

F. J. Salguero, A. D. White, G. S. Slack, S. A. Fotheringham, K. R. Bewley, K. E. Gooch, S. Longet, H. E. Humphries, R. J. Watson, L. Hunter, K. A. Ryan, Y. Hall, L. Sibley, C. Sarfas, L. Allen, , Tr

This study compares rhesus and cynomolgus macaques as models for mild to moderate COVID-19, showing similar viral replication, immune responses, and histopathology.

bioRxiv · Sep 17, 2020Microbiology

A burning question: Can savannah fire management generate enough carbon revenue to help save the lion from extinction?

T. Tear, N. H. Wolff, G. L. Lipsett-Moore, M. E. Ritchie, N. S. Ribeiro, L. S. Petracca, P. A. Lindsey, L. Hunter, A. J. Loveridge, F. Steinbruch

This paper estimates carbon revenue from savanna fire management to fund lion conservation in Africa, finding potential revenues of $59.6-$1.7B/year at $5-$13/ton.

bioRxiv · Jun 4, 2020 · PreprintEcology

Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge

K. A. Ryan, K. R. Bewley, S. A. Fotheringham, P. Brown, Y. Hall, A. C. Marriott, J. A. Tree, L. Allen, M. J. Aram, E. Brunt, K. R. Buttigieg, B. E. Cavell, D. P. Carter, R. Cobb, N. S. Coombes, , M Dennis

This study investigates the dose-dependent response of ferrets to SARS-CoV-2 infection, showing protection against re-challenge and mild clinical disease.

bioRxiv · May 29, 2020Microbiology

Constitutive TRIM22 expression within the respiratory tract identifies tissue-specific and cell-type dependent intrinsic immune barriers to influenza A virus infection

M. Charman, S. McFarlane, J. K. Wojtus, E. Sloan, R. Dewar, G. Leeming, M. Al-Saadi, L. Hunter, M. Carroll, J. P. Stewart, P. Digard, E. Hutchinson, C. Boutell

This study identifies TRIM22 as a constitutively expressed antiviral factor in the respiratory tract that restricts influenza A virus infection independently of cytokine-mediated immunity.

bioRxiv · Jun 21, 2019 · PreprintImmunology