Author

G. Lolli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Astolfi· 1 shared A. Bisio· 1 shared A. Boldrini· 1 shared A. Caflisch· 1 shared A. Ianeselli· 1 shared A. J. Holland· 1 shared A. Mattivi· 1 shared B. Vignoli· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

A. Astolfi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores

M. Burigotto, V. Vigorito, A. Mattivi, C. Gliech, S. Ghetti, A. Bisio, G. Lolli, A. J. Holland, L. L. Fava

The paper shows that PLK1-dependent displacement of 53BP1 from kinetochores is essential for mitotic surveillance pathway activity.

bioRxiv · Mar 27, 2023Cell Biology

PHARMACOLOGICAL PROTEIN INACTIVATION BY TARGETING FOLDING INTERMEDIATES

G. Spagnolli, T. Massignan, A. Astolfi, S. Biggi, P. Brunelli, M. Libergoli, A. Ianeselli, S. Orioli, A. Boldrini, L. Terruzzi, G. Maietta, M. Rigoli, N. Lopez Lorenzo, L. C. Fernandez, L. Tosatto, , E. Biasini

The paper discovers non-native metastable states in protein folding pathways and develops a novel drug discovery approach, PPI-FIT, to target these intermediates to lower protein expression.

bioRxiv · Mar 31, 2020 · PreprintBiochemistry

Discovery of BAZ2A Bromodomain Ligands

D. Spiliotopoulos, E.-C. Wamhoff, G. Lolli, C. Rademacher, A. Caflisch

The paper identifies BAZ2A bromodomain ligands through high-throughput screening and validates their binding using NMR and crystal structures.

bioRxiv · Jun 7, 2017Biochemistry