Author

S. Ghetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Musacchio· 2 shared L. L. Fava· 2 shared A. Bisio· 1 shared A. Borsellini· 1 shared A. Graziadei· 1 shared A. J. Holland· 1 shared A. Mattivi· 1 shared A. Mazouzi· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. Musacchio

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Drug-repurposing screen identifies thiostrepton as a novel regulator of the tumor suppressor DAB2IP

R. De Florian Fania, S. Maiocchi, R. Klima, V. Pellegrini, S. Ghetti, D. Selvestrel, L. L. Fava, L. Braga, L. Collavin

The paper screens FDA-approved drugs to find those that increase DAB2IP protein levels, identifying thiostrepton as a potential anti-cancer agent that relies on DAB2IP for its tumor-suppressive effect.

bioRxiv · Jul 12, 2024Cancer Biology

Interplay of kinetochores and catalysts drives rapid assembly of the mitotic checkpoint complex

S. Sethi, V. Piano, S. Ghetti, V. Cmentowski, P. Stege, A. Musacchio

The paper investigates how kinetochores facilitate the rapid assembly of the mitotic checkpoint complex (MCC) by co-orienting SAC catalysts in vitro.

bioRxiv · Jun 9, 2024Biochemistry

Condensin II activation by M18BP1

A. Borsellini, D. Conti, E. Cutts, R. J. Harris, K. Walstein, A. Graziadei, V. Cecatiello, T. F. Aarts, R. Xie, A. Mazouzi, S. Sen, C. Hoencamp, R. Pleuger, S. Ghetti, L. Oberste-Lehn, , A. Vannini

The paper identifies M18BP1 as a factor required for condensin II localization to chromatin and shows it competes with MCPH1 to activate condensin II during mitosis.

bioRxiv · May 2, 2024Cell Biology

Spatiospectral image processing workflow considerations for advanced MR spectroscopy of the brain

L. Y. Cai, S. N. Del Tufo, L. Barquero, M. D'Archangel, L. Sachs, L. Cutting, N. Glaser, S. Ghetti, S. S. Jaser, A. W. Anderson, L. C. Jordan, B. A. Landman

The paper describes a framework for processing advanced MR spectroscopy data, integrating with LCModel to improve spatial and spectral analysis of brain metabolites.

bioRxiv · Sep 7, 2023 · PreprintBioengineering

The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores

M. Burigotto, V. Vigorito, A. Mattivi, C. Gliech, S. Ghetti, A. Bisio, G. Lolli, A. J. Holland, L. L. Fava

The paper shows that PLK1-dependent displacement of 53BP1 from kinetochores is essential for mitotic surveillance pathway activity.

bioRxiv · Mar 27, 2023Cell Biology