Author

G. Muthukumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Guna· 2 shared A. J. Inglis· 2 shared J. S. Weissman· 2 shared R. M. Voorhees· 2 shared T. A. Stevens· 2 shared T. K. Esantsi· 2 shared A. N. Pogson· 1 shared B. Lomenick· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

A. Guna

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Author profile →

2 papers

Recent·Most cited

Triaging of -helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology

G. Muthukumar, T. A. Stevens, A. J. Inglis, T. K. Esantsi, R. A. Saunders, F. Schulte, R. M. Voorhees, A. Guna, J. S. Weissman

The paper identifies distinct chaperone machinery for targeting mitochondrial outer membrane -helical proteins based on their topology using CRISPRi screens and biochemical analysis.

bioRxiv · Aug 16, 2023Cell Biology

MTCH2 is a mitochondrial outer membrane protein insertase

A. Guna, T. A. Stevens, A. J. Inglis, J. M. Replogle, T. K. Esantsi, G. Muthukumar, K. C. L. Shaffer, M. L. Wang, A. N. Pogson, J. J. Jones, B. Lomenick, T.-F. Chou, J. S. Weissman, R. M. Voorhees

The paper identifies MTCH2 as an insertase required for mitochondrial TA protein insertion and shows its role in controlling TA localization and apoptosis sensitivity.

bioRxiv · Sep 15, 2022Cell Biology