Author

T. A. Stevens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1

Frequent Co-Authors

R. M. Voorhees· 3 shared A. Guna· 2 shared A. J. Inglis· 2 shared G. Muthukumar· 2 shared J. S. Weissman· 2 shared T. K. Esantsi· 2 shared A. Hoelz· 1 shared A. N. Pogson· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

R. M. Voorhees

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Triaging of -helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology

G. Muthukumar, T. A. Stevens, A. J. Inglis, T. K. Esantsi, R. A. Saunders, F. Schulte, R. M. Voorhees, A. Guna, J. S. Weissman

The paper identifies distinct chaperone machinery for targeting mitochondrial outer membrane -helical proteins based on their topology using CRISPRi screens and biochemical analysis.

bioRxiv · Aug 16, 2023Cell Biology

A nanobody-based strategy for rapid and scalable purification of native human protein complexes

T. A. Stevens, G. P. Tomaleri, M. Hazu, S. Wei, V. N. Nguyen, C. DeKalb, R. M. Voorhees, T. Pleiner

This paper introduces a method for rapidly purifying native human protein complexes using nanobodies and lentiviral transduction, achieving high purity and yield in ~8 days.

bioRxiv · Mar 9, 2023Biochemistry

MTCH2 is a mitochondrial outer membrane protein insertase

A. Guna, T. A. Stevens, A. J. Inglis, J. M. Replogle, T. K. Esantsi, G. Muthukumar, K. C. L. Shaffer, M. L. Wang, A. N. Pogson, J. J. Jones, B. Lomenick, T.-F. Chou, J. S. Weissman, R. M. Voorhees

The paper identifies MTCH2 as an insertase required for mitochondrial TA protein insertion and shows its role in controlling TA localization and apoptosis sensitivity.

bioRxiv · Sep 15, 2022Cell Biology

Architecture of the linker-scaffold in the nuclear pore

S. Petrovic, D. Samanta, T. Perriches, C. J. Bley, K. Thierbach, B. Brown, S. Nie, G. W. Mobbs, T. A. Stevens, X. Liu, A. Hoelz

The paper establishes the near-atomic molecular architecture and evolutionary conservation of the linker-scaffold in the human nuclear pore complex.

bioRxiv · Oct 26, 2021Biochemistry