Author

G. Orend

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Klein· 1 shared A. M. Astudillo· 1 shared A. Mechine-Neuville· 1 shared C. Spenle· 1 shared D. Guenot· 1 shared E. Mammadova-Bach· 1 shared E. Pencreach· 1 shared G. Cremel· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Klein

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2 papers

Recent·Most cited

ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting

L. Albacete-Albacete, I. Navarro-Lerida, J. A. Lopez, I. Martin-Padura, A. M. Astudillo, M. Van-Der-Heyden, J. Balsinde, G. Orend, J. Vazquez, M. A. del Pozo

This study shows caveolin-1 regulates exosome biogenesis and cargo sorting, driving ECM deposition and tumor cell invasiveness through cholesterol-dependent mechanisms.

bioRxiv · Sep 5, 2018Cell Biology

Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma

E. Mammadova-Bach, T. Rupp, C. Spenle, I. Jivkov, P. P. Shankaranarayanan, A. Klein, L. Pisarsky, A. Mechine-Neuville, G. Cremel, M. Kedinger, O. De Wever, N. Ambartsumian, S. Robine, E. Pencreach, D. Guenot, , O. Lefebvre

This study shows that laminin α1 promotes colon tumor growth by facilitating VEGFA-driven angiogenesis through interactions with integrin β1 and CXCR4.

bioRxiv · Jan 10, 2017Cancer Biology