Cell BiologybioRxiv
ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting
L. Albacete-Albacete, I. Navarro-Lerida, J. A. Lopez…·M. A. del Pozo
This study shows caveolin-1 regulates exosome biogenesis and cargo sorting, driving ECM deposition and tumor cell invasiveness through cholesterol-dependent mechanisms.
DOI 10.1083/jcb.202006178