Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.
A. Natalini, S. Simonetti, G. Favaretto, L. Lucantonio, G. Peruzzi, M. Munoz-Ruiz, G. Kelly, A. M. Contino, R. Sbrocchi, S. Battella, S. Capone, A. Folgori, A. Nicosia, A. Santoni, A. C. Hayday, F. Di Rosa
The study shows that a delayed vaccine boost at day 100 post-prime enhances CD8 T cell memory response compared to day 30, with a distinct molecular signature in splenic cells.
bioRxiv · Aug 4, 2022Immunology