Author

S. Capone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

A. Folgori· 5 shared A. Leuzzi· 2 shared A. M. Contino· 2 shared A. Natalini· 2 shared A. Nicosia· 2 shared A. Santoni· 2 shared A. Vitelli· 2 shared F. Di Rosa· 2 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

A. Folgori

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates

J. I. Moliva, S. F. Andrew, B. J. Flynn, D. A. Wagner, K. E. Foulds, M. Gagne, D. R. Flebbe, E. Lamb, S. Provost, J. Marquez, A. Mychalowych, C. Lorag, C. C. Honeycutt, M. R. Burnett, L. McCormick, , Nason

This study shows a gorilla adenovirus-based vaccine provides durable immunity against SARS-CoV-2 in both airways of non-human primates, with enhanced protection from aerosol delivery and prime-boost regimens.

bioRxiv · Nov 22, 2023 · PreprintImmunology

Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.

A. Natalini, S. Simonetti, G. Favaretto, L. Lucantonio, G. Peruzzi, M. Munoz-Ruiz, G. Kelly, A. M. Contino, R. Sbrocchi, S. Battella, S. Capone, A. Folgori, A. Nicosia, A. Santoni, A. C. Hayday, F. Di Rosa

The study shows that a delayed vaccine boost at day 100 post-prime enhances CD8 T cell memory response compared to day 30, with a distinct molecular signature in splenic cells.

bioRxiv · Aug 4, 2022Immunology

Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19

A. Vitelli, S. Capone, A. Raggioli, M. Gentile, S. Battella, A. Lahm, A. Sommella, A. M. Contino, R. A. Urbanowicz, R. Scala, F. Barra, A. Leuzzi, E. Lilli, G. Miselli, A. Noto, , S. Colloca

This paper evaluates a gorilla adenovirus vaccine candidate for COVID-19, showing it is immunogenic in mice and macaques and supports its advancement to a Phase I clinical trial.

bioRxiv · Oct 22, 2020Immunology

Activation of MAIT cells plays a critical role in viral vector vaccine immunogenicity

N. Provine, A. Amini, L. Garner, C. Dold, C. Hutchings, M. FitzPatrick, L. Silva Reyes, S. Chinnakannan, B. Oguti, M. Raymond, S. Capone, A. Folgori, C. Rollier, E. Barnes, A. Pollard, P. Klenerman

This study shows that MAIT cell activation is essential for the immunogenicity of adenovirus vector vaccines, as it drives HCV-specific CD8 T cell responses.

bioRxiv · Jun 13, 2019 · PreprintImmunology

A previously missed population of antigen-specific CD8 T cells divides in the blood after vaccination

S. Simonetti, A. Natalini, A. Folgori, S. Capone, A. Nicosia, A. Santoni, F. Di Rosa

bioRxiv · Aug 14, 2018Immunology

Comprehensive characterization of pediatric AML reveals diverse fusion oncoproteins and age-specific mutational interactions

H. Bolouri, J. E. Farrar, T. J. Triche, R. E. Ries, E. L. Lim, T. A. Alonzo, Y. Ma, R. Moore, A. Mungall, M. A. Marra, J. Zhang, X. Ma, Y. Liu, Y. Liu, J. M. Guidry Auvil, , S. Meshinchi

This study characterizes the molecular landscape of pediatric AML, identifying age-specific mutations and fusion oncoproteins that differ from adult AML.

bioRxiv · Oct 10, 2017Cancer Biology