Author

F. Bartolini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Assay:electronic health records· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Kumar· 2 shared A. Indrieri· 1 shared A. Klestzick· 1 shared A. Oza· 1 shared C. Hachicho· 1 shared C. L. Vizcarra· 1 shared C. M. Rojas· 1 shared C. Sanchini· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

A. Kumar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with alpha-tubulin acetylation and is disrupted in CMT2A

A. Kumar, D. Larrea, M. E. Pero, P. Infante, M. Conenna, G. J.-e. Shin, W. B. Grueber, L. Di Marcotullio, E. Area-Gomez, F. Bartolini

This paper shows that MFN2 recruits ATAT1 to mitochondria to regulate microtubule acetylation and mitochondria transport, and that CMT2A mutations disrupt this process leading to axonal degeneration.

bioRxiv · Mar 15, 2023 · PreprintCell Biology

Alterations to the broad-spectrum formin inhibitor SMIFH2 improve potency

M. Orman, M. Landis, A. Oza, D. Nambiar, J. Gjeci, K. Song, V. Huang, A. Klestzick, C. Hachicho, S. Q. Liu, J. M. Kamm, F. Bartolini, J. J. Vadakkan, C. M. Rojas, C. L. Vizcarra

The paper tests SMIFH2 and its derivatives against human formins, finding that modifications enhance potency but do not allow distinction between conserved FH2 domains.

bioRxiv · Mar 10, 2022 · PreprintBiochemistry

Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays

M. Rosito, C. Sanchini, G. Gosti, M. Moreno, S. De Panfilis, M. Giubettini, D. Debellis, F. Catalano, G. Peruzzi, R. Marotta, A. Indrieri, E. De Leonibus, M. E. De Stefano, D. Ragozzino, G. Ruocco, , F. Bartolini

This study shows that reactive microglia undergo microtubule remodeling from acentrosomal to centrosomal arrays, linking this change to inflammatory responses.

bioRxiv · Feb 21, 2022Cell Biology

Activity-dependent nucleation of dynamic microtubules at presynaptic boutons is required for neurotransmission

X. Qu, A. Kumar, H. Blockus, C. Waites, F. Bartolini

The paper shows that activity-dependent MT nucleation at presynaptic boutons is essential for neurotransmission by enabling SV transport and exocytosis.

bioRxiv · Jun 21, 2019Cell Biology