Author

S. Simonetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Folgori· 2 shared A. Natalini· 2 shared A. Nicosia· 2 shared A. Santoni· 2 shared F. Di Rosa· 2 shared I. Casanova-Salas· 2 shared J. Carles· 2 shared J. Mateo· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

A. Folgori

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Author profile →

5 papers

Recent·Most cited

Evaluation of homologous recombination repair status in metastatic prostate cancer by next-generation sequencing and functional tissue-based immunofluorescence assays

S. Arce-Gallego, P. C. Morgado, L. Delgado-Serrano, S. Simonetti, M. Gonzalez, D. Marmolejo, R. Morales-Barrera, G. Mir, M. E. Semidey, P. R. Lozano, S. Cordoba-Terreros, R. Mast, M. de Albert, J. Planas, M. Cuadras, , J. Mateo

This study evaluates homologous recombination repair status in metastatic prostate cancer using next-generation sequencing and RAD51 immunofluorescence assays, finding strong correlation between genomic and functional HRR loss.

bioRxiv · Jan 28, 2024Cancer Biology

Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution

I. Casanova-Salas, S. Cordoba-Terreros, D. Aguilar, L. Agundez, J. Brandariz, N. Herranz, M. Gonzalez, R. Morales-Barrera, A. Sierra, M. Soriano-Navarro, P. Cresta, S. Simonetti, G. Rodrigues, S. Arce-Gallego, L. Delgado, , J. Mateo

This study shows that circulating tumor extracellular vesicles can be used to monitor genomic and transcriptomic changes in metastatic prostate cancer through liquid biopsy.

bioRxiv · Apr 14, 2023Cancer Biology

Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.

A. Natalini, S. Simonetti, G. Favaretto, L. Lucantonio, G. Peruzzi, M. Munoz-Ruiz, G. Kelly, A. M. Contino, R. Sbrocchi, S. Battella, S. Capone, A. Folgori, A. Nicosia, A. Santoni, A. C. Hayday, F. Di Rosa

The study shows that a delayed vaccine boost at day 100 post-prime enhances CD8 T cell memory response compared to day 30, with a distinct molecular signature in splenic cells.

bioRxiv · Aug 4, 2022Immunology

Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cells

G. Serra-Bardenys, T. V. Tian, E. Blanco, J. Querol, L. Pascual-Reguant, B. Morancho, M. Escorihuela, S. Segura-Bayona, G. Verde, R. Aiese Cigliano, A. Millanes-Romero, C. Jerónimo, P. Nuciforo, S. Simonetti, C. Viaplana, , S. Peiró

This study identifies the role of H3K4ox in maintaining heterochromatin structure in TNBC cells and shows its necessity for oncogenic properties.

bioRxiv · Jan 30, 2020 · PreprintCancer Biology

A previously missed population of antigen-specific CD8 T cells divides in the blood after vaccination

S. Simonetti, A. Natalini, A. Folgori, S. Capone, A. Nicosia, A. Santoni, F. Di Rosa

bioRxiv · Aug 14, 2018Immunology