Self-assembly of pericentriolar material in interphase cells lacking centrioles
F. Chen, J. Wu, M. K. Iwanski, D. Jurriens, A. Sandron, M. Pasolli, G. Puma, J. Z. Kromhout, C. Yang, W. Nijenhuis, L. C. Kapitein, F. Berger, A. Akhmanova
This study shows that PCM can self-assemble into a compact MTOC in interphase cells without centrioles, using dynein transport and self-clustering, but this process is sensitive to motor and microtubule dynamics.
bioRxiv · Aug 22, 2021Cell Biology