Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer
A. U. Schirmer, L. M. Driver, M. T. Zhao, C. I. Wells, J. E. Pickett, S. N. O'Bryne, B. J. Eduful, X. Yang, L. Howard, S. You, G. R. Devi, J. Digiovanni, S. F. Freedland, J.-T. A. Chi, D. Drewry, E. Macias
This study shows that STK3, typically a tumor suppressor, promotes prostate cancer growth and identifies STK3 inhibitors with therapeutic potential.
bioRxiv · Feb 21, 2021Cancer Biology