Author

G. S. Shaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Walden· 2 shared K. M. Dunkerley· 2 shared A. C. Rintala-Dempsey· 1 shared D. Hadi· 1 shared E. A. Freeman· 1 shared G. Salzano· 1 shared J. Aguirre· 1 shared K. Barber· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

H. Walden

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 1, 2021

Distinct phosphorylation signals drive acceptor versus self-ubiquitination selection by Parkin

K. M. Dunkerley, A. C. Rintala-Dempsey, G. Salzano…·G. S. Shaw

This study shows parkin uses distinct phosphorylation signals for ubiquitinating acceptor proteins versus self-ubiquitination, with phosphorylation triggering autoubiquitination.

DOI 10.1101/2021.06.01.446590

proteomicsexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivJun 12, 2018

Synergistic Recruitment of UbcH7~Ub and Phosphorylated Ubl Domain Triggers Parkin Activation

T. E. Condos, K. M. Dunkerley, E. A. Freeman…·G. S. Shaw

This study reveals how phosphorylation and ubiquitin binding synergistically activate parkin by reorganizing its structure to facilitate ubiquitin transfer.

DOI 10.15252/embj.2018100014

protein structureexperimental assay

𝕏 PostBluesky