Influence of genetic ancestry on breast stromal cells provides biologic basis for increased incidence of metaplastic breast cancer in women of African descent
B. Kumar, K. Batic, P. Bhat-Nakshatri, M. M. Granatir, R. J. Addison, M. Szymanski, L. A. Baldridge, C. J. Temm, G. Sandusky, S. K. Althouse, A. M. Storniolo, H. Nakshatri
The paper identifies PZP stromal cells enriched in African Ancestry women that may contribute to metaplastic breast cancer incidence through epithelial communication and STAT3 activation.
Nature Communications · Sep 14, 2023Peer-reviewedCancer Biology