Cancer BiologybioRxivPreprint
Bromodomain 4 inhibition leads to MYCN downregulation in Wilms' tumor cells
A. D. Woods, C. Keller, N. E. Berlow…·R. Veselska
This study shows that BRD4 inhibition reduces MYCN levels and suppresses proliferation in Wilms tumor cells, suggesting AZD5153 as a potential therapeutic agent.
DOI 10.1101/2021.01.04.425208