Author

G. Vedantam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:C. elegans· 2 Assay:metagenomics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. A. P. Roxas· 2 shared F. Anwar· 2 shared K. E. Carothers· 2 shared V. K. Viswanathan· 2 shared V. Viswanathan· 2 shared A. E. Clark· 1 shared B. Roxas· 1 shared B. Trindade· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

B. A. P. Roxas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A superoxide reductase contributes to Clostridioides difficile resistance to oxygen

R. Kochanowsky, K. E. Carothers, B. Roxas, F. Anwar, V. Viswanathan, G. Vedantam

This study identifies a superoxide reductase (SOR) in C. difficile that contributes to its resistance to oxygen and oxidative stress.

bioRxiv · Dec 19, 2022 · PreprintMicrobiology

Low-Toxin Clostridioides difficile RT027 Strains Exhibit Robust Virulence

F. Anwar, B. A. P. Roxas, K. W. Shehab, N. Ampel, V. K. Viswanathan, G. Vedantam

The paper investigates low-toxin RT027 C. difficile strains and finds they exhibit robust virulence despite being toxin-negative by NAAT, challenging current diagnostic assumptions.

bioRxiv · Mar 18, 2022Microbiology

The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties

A. E. Clark, C. C. Adamson, K. E. Carothers, B. A. P. Roxas, V. Viswanathan, G. Vedantam

This study shows that SigL, an alternative sigma factor in C. difficile, affects toxin production, sporulation, and cell surface properties differently in two strains.

bioRxiv · Jan 26, 2022Microbiology

Nonsteroidal anti-inflammatory drugs alter the microbiota and exacerbate Clostridium difficile colitis while dysregulating the inflammatory response

D. Maseda, J. P. Zackular, B. Trindade, L. Kirk, L. J. Crofford, P. D. Schloss, J. L. Roxas, V. K. Viswanathan, G. Vedantam, L. M. Rogers, M. K. Washington, E. P. Skaar, D. M. Aronoff

This study shows NSAIDs like indomethacin alter gut microbiota and worsen C. difficile colitis by disrupting PG metabolism, epithelial integrity, and immune responses in mice.

bioRxiv · Aug 14, 2018Microbiology