Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation
C. Wu, X. Cai, Y. Wang, C. D. Rodriguez, L. Herrmann, G. Zoaldi, C.-Y. Huang, X. Wang, V. R. Sanghvi, R. O. Lu, Z. Meng
This study identifies RAP2 GTPase as a central integrator of cytoskeletal signals in Hippo pathway regulation, showing its role in mediating responses to cytoskeletal changes and its impact on Hippo kinase activity.
bioRxiv · Oct 10, 2023Cell Biology